How Cannabis May Help Treat Gastritis
Cannabis can be an effective, natural, and safe treatment against gastritis. The herb contains cannabinoids, that bind to CB1 receptors within the gut, resulting in tissue repair.
Modern science is unveiling how cannabis can work within the human body in a very specific way in order to successfully treat and possibly even cure a wide variety of illnesses, ailments, and conditions. One condition, that the herb seems to help treat is gastritis, a group of symptoms, that are all caused by inflammation of the gut.
WHAT IS GASTRITIS?
Gastritis is characterised by inflammation occurring within the gut, and can manifest in multiple forms. The inflammation at the root of the condition is most commonly caused by a strain of bacteria known as Helicobacter pylori, which is one of the most common bacterial infections. However, only a select amount of people who become infected by the bacteria suffer with symptoms of gastritis. This could be because of numerous factors, including genetics, lifestyle, and environmental factors.
When it comes to lifestyle choices, gastritis can spring up after the use of alcohol, spicy foods, anti-inflammatory drugs, autoimmune issues, radiation therapy, and Crohn’s disease.
These factors can lead to inflammation of the gut lining, leading to inflammation of the mucosa. The condition can eventually damage this protective layer, leading to stomach acid damaging the stomach lining.
TYPES OF GASTRITIS
Gastritis, that appears suddenly is known as acute gastritis and can be directly linked to the use of non-steroidal anti-inflammatory drugs (NSAIDS). This is due to inhibition of an enzyme, that is responsible for synthesis of eicosanoids within the stomach, which can lead to the formation of stomach ulcers. Drugs such as aspirin can also lead to reduced production of prostaglandin, which actively helps to protect the stomach. Physiological stress from hypoxia and trauma can also lead to acute gastritis.
Gastritis, that appears slowly over a long period of time, is known as chronic gastritis. This can be caused by autoimmune disorders, where the body creates proteins and antibodies, that perceive the stomach as a foreign threat and begin to attack and deteriorate the stomach lining. Autoimmune gastritis is more common in patients experiencing Hashimoto’s disease, type 1 diabetes, and vitamin B12 deficiency.
Chronic gastritis can also be caused by bile making its way into the stomach, connective tissue disorders, and liver or kidney failure.
Old age is also a contributing factors, considering, that the stomach lining tends to thin with age, and the older population is more likely to experience Helicobacter pylori infections than the younger population.
SYMPTOMS OF GASTRITIS
Gastritis can lead to an array of uncomfortable symptoms, which can in some cases eventually lead to stomach ulcers and even an increased risk of stomach cancer. One major symptom of the condition is a burning ache or pain, that manifests in the stomach region and within the upper abdomen. Other symptoms include nausea, vomiting, bloating, belching, indigestion, and loss of appetite.
HOW CANNABIS CAN HELP
Avoiding certain foods, such as acidic fruits and high-fat food may help with the condition, along with halting lifestyle habits such as smoking, consuming caffeine, and drinking excessive amounts of alcohol.
Certain antibiotics may also be used in order to target Helicobacter pylori bacteria. However, such medications may actually result in side effects, that are similar to the symptoms of gastritis itself, such as nausea, vomiting, loss of appetite, and abdominal pain.
Cannabis is a safe and natural medicine, that acts as an excellent option for some people that are dealing with the condition. The herb can offer some of the benefits of conventional medicines used for the condition, yet without many of the damaging and uncomfortable side effects, that can reduce the patient’s quality of life.
Cannabis can act to reduce some of the symptoms caused by the condition, and may actually act at a deeper level to quell the inflammation at the root cause of gastritis.
Cannabis is well known to assist in nausea and vomiting, two symptoms of gastritis. THC, a psychoactive cannabinoid within the cannabis plant, has been prescribed since the 1980s for the treatment of nausea, and is often employed to combat it after bouts of chemotherapy. Its effectiveness is believed to be linked to how the cannabinoids effect centres within the brain, that control both nausea and vomiting.
Loss of appetite is another symptom of gastritis, and one, that cannabis can definitely assist with. The plant is associated with the famous stereotype of inducing the “munchies”, a ravenous appetite, that can occur after ingesting THC, resulting in the raiding of many fridges.
Research has shown that gastritis is associated with mood disorders, such as anxiety, panic attacks and depression. Cannabis is commonly prescribed for these mental conditions and may be of great assistance to gastritis patients who are suffering from them.
As we have discussed, the primary cause of gastritis is inflammation of the gut lining. Cannabis produces numerous cannabinoids with potent and proven anti-inflammatory properties, such as CBD.
What’s more, a 2005 study conducted at the University of Bath and Bristol in the United Kingdom, showed that cannabis is effective in cases of inflammatory bowel disease and gastritis. The researches explained that cannabis influenced cannabinoid receptors within the gut and brain, resulting in effective treatment.
Cannabinoid receptors can be found all throughout the body, and make up what is known as the endocannabinoid system. These receptors are activated by numerous cannabinoids within the cannabis plant. The endocannabinoid system is partly made up of CB1 receptors, which can be found within the brain and the lining of the gut. These receptors are reported to help repair the gut lining when it becomes damaged.
During the study, researchers purposely damaged gut tissue, resulting in inflammation. Synthetic cannabinoids were then administered to the tissue, resulting in the healing process. It is believed, that cannabinoids created within the body, or endocannabinoids, are released from endothelial cells of a healthy gut, which go on to bind to CB1 receptors and assist in the repair process when damage occurs. When patients use medical cannabis, external cannabinoids may help to fulfil the same purpose.
Cannabis has been shown to be effective at helping to repair the gut when it comes to gastritis, activating CB1 receptors within the region.
Best CBD Oil for Gastritis – November 2020
Does CBD Work for Gastritis?
- Research in 2020 revealed that cannabidiol (CBD) had anti-inflammatory effects in rodent models of intestinal inflammation (1) . Gastritis is an inflammation of the stomach lining (2) .
- A systematic review in 2019 suggested that CBD had anti-inflammatory and antioxidant properties (3) .
- A preclinical study in the British Journal of Pharmacology stated that CBD might be promising in alleviating vomiting and nausea caused by treatments, such as chemotherapy (4) . Vomiting and nausea are common gastritis symptoms (5) .
- Currently, the animal and human studies available focus on CBD’s effects on symptoms associated with gastritis.
- More research on CBD’s benefits on gastritis is warranted.
Spruce 750mg Lab Grade CBD Oil
Specifically formulated to be more palatable to CBD users
Overall Clinical Score
Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.
-   Natural peppermint flavor
-   Made from 100% organic and natural ingredients
-   No other flavors
|Discount pricing available?||20% Off Coupon Code: CBDCLINICALS|
NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
Perfect for anyone who are looking for CBD products that promote a healthy body and mind.
Overall Clinical Score
Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.
-   Pure CBD hemp
-   All natural
-   Approximately 300 drops total
-   No other flavors
|Discount pricing available?||20% Off Coupon Code: CBDCLINICALS20|
Sabaidee Super Good Vibes CBD Oil
4x the strength of a regular cbd oil
Overall Clinical Score
Super Good Vibes CBD Oil provides the purest and highest quality Cannabidiol (CBD) on the market as well as other high quality phytocannabinoids, terpenes, vitamins, omega fatty acids, trace minerals, and other beneficial for your health elements, which all work together to provide benefits.
-   Extra strong
-   Significant benefits with just a few drops
-   100% Natural ingredients
-   No other flavors
|Discount pricing available?||15% Off Coupon Code: CBDCLINICALS15|
cbdMD CBD Oil Tincture Natural 1500mg
Uses USA hemp that is grown on non-GMO farms, and is both vegan and gluten-free
Overall Clinical Score
cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.
-   Various delicious flavors to choose from
-   Has vegan, organic, and gluten-free ingredients
-   Free shipping for this particular product within USA
-   World-class customer service team
-   cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
|Discount pricing available?||15% Off Coupon Code: cbdMD15|
Why People Are Taking CBD for Gastritis
Commonly prescribed medications and over-the-counter drugs for gastritis include omeprazole, rabeprazole, lansoprazole, dexlansoprazole, esomeprazole, and pantoprazole (6) . These drugs are some of the most potent inhibitors of stomach acid.
However, these medications may have side effects , such as iron and B12 deficiency, increased risk of fractures, pneumonia, and Clostridium difficile infections (7) . They can also be quite expensive over the long-term.
Clostridium difficile infections may cause diarrhea and eventually develop into a life-threatening medical condition .
Doctors may also prescribe antacids to treat gastritis by neutralizing stomach acid and providing pain relief. However, these drugs may result in constipation or diarrhea (8) .
A 2020 study in the International Journal of Molecular Sciences outlined CBD’s role in preventing and treating gastrointestinal disorders, like irritable bowel syndrome (IBS) and gastrointestinal cancer (9) .
The study demonstrated CBD’s anti-inflammatory properties in mice models of intestinal inflammation.
Gastritis is a collective term that refers to the inflammation of the lining of the stomach (10) .
Research in the Journal of Molecular Medicine evaluated CBD’s effects on an inflammatory bowel disease like ulcerative colitis (11) .
The authors found that CBD had anti-inflammatory properties beneficial for the inflamed gut. They also reported that CBD, a “likely safe compound,” prevented experimental colitis in mice.
Despite CBD’s purported health benefits on the digestive tract , it is essential to note the side effects of CBD use. These effects include diarrhea, changes in appetite or weight, and tiredness (12) .
CBD for Inflammation
A 2019 review archived in the journal Antioxidants stated that CBD had anti-inflammatory and antioxidant properties (13) .
The authors also mentioned CBD’s promise in treating disorders associated with inflammation and oxidative stress, such as cancer, cardiovascular, metabolic, and neurodegenerative diseases.
Another study documented in the journal Future Medicinal Chemistry discussed CBD’s effects on non-obese and diabetes-prone female rodents (14) .
The researchers found that CBD had anti-inflammatory effects that could help prevent type 1 diabetes.
CBD for Nausea
Common symptoms of gastritis include nausea and vomiting (15) .
Preclinical research showed that CBD might be useful in treating vomiting and nausea caused by chemotherapy and other treatments (16) .
A study archived in the British Journal of Clinical Pharmacology evaluated the effects of a dose containing CBD and tetrahydrocannabinol (THC) on patients with chemotherapy-induced nausea and vomiting (17) .
The researchers found that CBD and THC were well-tolerated and had antiemetic (vomit-preventing) properties.
They also observed that patients who received the cannabis-based medicine had better protection against delayed chemotherapy-induced nausea and vomiting.
CBD and THC are derived from the Cannabis sativa plant. However, unlike CBD, THC may get individuals high because of its psychoactive properties.
THC mainly comes from marijuana, a variant of the cannabis plant. Despite THC’s suggested benefits, medical marijuana use is not legal in the entire United States (18) .
CBD for Ulcers
Untreated gastritis may result in stomach ulcers and bleeding or stomach perforation (19) .
A 2018 study in the journal Phytotherapy Research evaluated CBD’s effects on oral wound healing (20) .
Standardized ulcers were induced in 60 rats. They were injected with 0mg (control), 5mg, and 10mg of CBD per kilogram of each rat’s body weight daily.
The researchers discovered that CBD had anti-inflammatory effects on the early phase of wound healing. However, they noted that their findings were insufficient to conclude that CBD use could improve oral traumatic lesions.
CBD as a Painkiller Substitute
The regular use of painkillers and nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, may result in gastritis and ulcers (21) .
Meanwhile, s tudies showed that CBD products might have analgesic effects. Hence, they may be used as substitutes for painkillers.
A study published in the journal Postgraduate Medicine revealed that CBD improved chronic pain in participants using opioids for pain management (22) .
One hundred thirty-one patients were included in the study. The researchers found that half of the study sample was able to reduce opioid use eight weeks after adding CBD to their medication regimen.
Participants who used CBD reported improvements in their quality of life. Their chronic pain and sleep quality also improved.
In another research, results indicated that CBD had analgesic and anxiolytic (anxiety-reducing) effects (23) .
Three hundred ninety-seven individuals were prescribed CBD. Participants who had non-cancer pain reported improvements in their pain.
Meanwhile, those who had mental health symptoms experienced alleviation of their depression and anxiety symptoms.
CBD was well-tolerated, and the participants did not report any adverse effects. Other CBD benefits include improved sleep and appetite.
How CBD Oil Works to Alleviate Symptoms of Gastritis
A study documented in the PLOS One Journal evaluated how CBD purportedly reduces intestinal inflammation (24) .
Eighteen participants were included in the study. The results revealed that CBD might interfere with enteroglial-mediated interactions in an intestinal inflammatory environment.
Enteric glial cells make up the enteric nervous system, a regulatory system responsible for gastrointestinal function (25) .
According to the study, CBD was involved in the downregulation of the protein S100B, resulting in reduced intestinal damage during acute and intestinal inflammation.
S100 proteins have a vital role in mediating innate and acquired immune response s (26) . These responses significantly contribute to the development of chronic inflammatory diseases.
It is believed that CBD’s interaction with the endocannabinoid system (ECS) may be related to its anti-inflammatory properties.
The ECS has an essential role in maintaining the body’s natural harmony. To fulfill this function, it interacts with several organs and systems in the body, such as the endocrine and immune systems (27) .
A study conducted in 2019 outlined the role of CBD and the ECS’ cannabinoid receptors in inflammation (28) .
Research found that CBD was a weak agonist of the cannabinoid receptor 1 ( CB1 receptor ) in humans and mice. It also stated that CBD demonstrated inverse agonism of the cannabinoid receptor 2 (CB2 receptor) .
An agonist is a substance that mimics another substance’s action, stimulating an action (29) .
The researchers found that the activation of cannabinoid receptor 2 reduces oxidative stress and inflammation.
They also found that CBD’s anti-inflammatory activity involved the reduction of cytokine levels, the inhibition of T-cell proliferation, the induction of T-cell apoptosis, and the migration of immune cells.
Cytokines are molecules that direct cell movement to sites of inflammation, trauma, and infection (30) .
T cells contribute to sustained inflammation by producing proinflammatory cytokines (31) .
Apoptosis is programmed cell death vital in removing unnecessary or abnormal cells (32) .
The Pros and Cons of CBD Oil for Gastritis
- Previous studies showed CBD’s positive effects on symptoms associated with gastritis and other conditions related to the digestive system .
- Compared with conventional drugs prescribed for gastritis, CBD’s safety profile is more favorable (33) .
- There are no reported cases of human or animal dependence on CBD (34) . Hence, individuals considering using CBD to treat their gastritis should not worry about developing a dependence on the substance.
- Researchers should further investigate CBD’s effects on gastritis.
- Despite the benefits of CBD , it still has side effects, such as diarrhea, tiredness, and changes in weight or appetite (35) .
- Policies from the United States Food and Drug Administration (US FDA ) do not support CBD as therapy for medical conditions other than epilepsy.
How CBD Oil Compares to Alternative Treatments for Gastritis
A study archived in the Sultan Qaboos University Medical Journal investigated honey’s antibacterial effects on the bacterium Helicobacter pylori ( H. pylori) , the common cause of several digestive issues, such as gastritis and a very common contributor to the development of gastric and duodenal ulcers (36) .
The researchers concluded that some honey brands had antibacterial properties useful in treating H. pylori infections.
They also noted that when honey was used with antibiotics, such as clarithromycin and amoxicillin, there was no synergy or antagonism.
They recommend that honey may be useful as an adjunct therapy. It helps reduce the elimination time of H. pylori bacteria from the stomach lining of individuals with gastritis or duodenal ulcer.
Similarly, CBD was found to have antibacterial properties. Research in 2019 reported CBD’s efficacy in killing a range of Gram-positive bacteria (37) .
The researchers suggested that, given CBD’s anti-inflammatory properties and proven safety in humans, the substance held promise as a new antibiotic.
They also noted how CBD retained its efficacy against bacteria that became highly resistant to other traditional antibiotics.
Gram-positive bacteria are called such because they give a positive result when put under the Gram stain test (38) .
How to Choose the Right CBD for Gastritis
A previously cited study showed the efficacy of THC or medical cannabis on gastritis symptoms, such as vomiting and nausea. However, as mentioned earlier, THC use is not legal in all US states.
Full-spectrum CBD oil contains all the Cannabis sativa plant components, including terpenes, flavonoids, fatty acids, essential oils, and trace amounts of THC.
It is suggested that full-spectrum oils provide full therapeutic benefits because of the synergy of all the active ingredients of the cannabis plant. This mechanism is called the entourage effect.
The THC content of full-spectrum CBD products (less than 0.30%) is allowed by federal laws. However, this minimal amount may still be detected by drug tests.
Individuals who want to purchase CBD products free of THC may buy broad-spectrum CBD. This type of CBD oil has all the ingredients of the full-spectrum oil except for THC.
For pure, isolated cannabidiol, CBD isolates may be purchased.
Full-spectrum CBD oils are recommended for gastritis treatment. Still, individuals are encouraged to speak to a medical professional before purchasing any CBD product.
It is also essential to research if a manufacturer or dispensary is credible and authorized by the government to sell CBD to avoid buying illegitimate products.
CBD Dosage for Gastritis
Currently, no standard dosage chart has been developed for CBD in treating gastritis. However, it is recommended to begin with a small amount of CBD .
If no adverse effects are seen, the dosage may be increased gradually until the desired effect is achieved.
Individuals using CBD for gastritis are encouraged to keep a journal of their reactions to the substance. They may refer to this journal during consultations with their physician.
Before adding CBD to one’s gastritis medication regimen, it is recommended to inform a medical professional first.
How to Take CBD for Gastritis
There are several options when taking CBD for gastritis.
Some formats, such as CBD oils and tinctures (drops), allow individuals to take CBD directly. Tinctures may be applied sublingually, or under the tongue, for added efficacy.
CBD oils may be mixed with food or beverages to mask CBD’s naturally grassy taste.
CBD pills, gelcaps, capsules, edibles, and gummies may be ingested. This format also allows people with gastritis to conveniently bring their CBD medication with them anywhere.
This format is also appropriate for people with gastritis problems who want to take a consistent dosage of CBD.
CBD topicals, such as balms, salves, lotions, and ointments, may also be used. During episodes of abdominal pain or upset stomach , these topicals may be massaged into the affected area.
Some topicals contain soothing ingredients, such as peppermint and menthol, for added pain relief.
For instantaneous effects, CBD may be inhaled via vape pens. However, vaping CBD may be challenging, as it is hard to determine how much CBD was already taken.
In some individuals, vaping may also cause lung problems (39) .
According to Johns Hopkins Medicine, gastritis occurs when the stomach lining gets swollen (40) .
Gastritis may be caused by drinking excessive amounts of alcohol, eating spicy food , extreme stress, smoking, and long-term use of pain and fever medications.
Bacterial infections , major surgeries, and traumatic injuries or burns may also cause gastritis.
Gastritis may be classified as acute gastritis or chronic gastritis . Gastritis symptoms include the following (41) :
- Stomach upset or pain
- Belching and hiccups
- Bloating or gas
- Bleeding of the belly or abdomen
- Loss of appetite
- Nausea and vomiting
- Blood in the vomit or stool
- Weight loss
When untreated, gastritis may also result in other more severe health complications. These conditions include peptic ulcer disease (painful sores in the upper digestive tract) and tumors that could lead to stomach cancer .
A study also found that gastritis was associated with an increased prevalence of panic attacks, social phobia, major depression, and mood disorders (42) .
Previously mentioned studies found that CBD might be useful in treating gastritis symptoms, such as inflammation, nausea, and pain.
Compared with conventional medications prescribed for gastritis, CBD is generally safe because of its minimal side effects.
Like honey, CBD was found to have antibacterial properties.
CBD also comes in different forms and formulations, giving individuals with gastritis several options.
While CBD has been deemed for its favorable safety profile, in some individuals, CBD oil may be hard on the stomach.
For a more efficient treatment, it is best to consult with a healthcare provider before taking any CBD product for gastritis.
Does CBD Work for Gastritis? Research in 2020 revealed that cannabidiol (CBD) had anti-inflammatory effects in rodent models of intestinal inflammation. Gastritis is an inflammation of the stomach lining.