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Capsaicin works by decreasing a certain natural substance in your body (substance P) that helps pass pain signals to the brain. If you have any questions, ask your doctor or pharmacist. For the cream, gel, and lotion forms, apply a thin layer of medication to the affected area and rub in gently and thoroughly. You may want to use a cotton ball/swab or latex glove to apply the medication to avoid touching the medication with your hands. Do not apply the medication in the eyes, mouth, nostrils, or genitals.

If you do get the medication in those areas, flush with plenty of water. Also, do not apply this medication to skin that is injured or irritated (for example, cut, scraped, sunburned). Do not apply this medication immediately before or after activities such as bathing, swimming, sun bathing, or heavy exercise. Do not bandage or wrap the affected area or use a heating pad on that area. After applying the medication, wash your hands unless you are using this medication to treat the hands. If treating the hands, wait at least 30 minutes after applying the medication to wash your hands. Use this medication regularly to get the most benefit from it.

To help you remember, use it at the same times each day. This medication may sometimes take up to 2 months to work. Tell your doctor if your condition persists for more than 7 days, if it worsens, or if it keeps returning. If you think you may have a serious medical problem, seek immediate medical attention. Warmth, stinging, or burning on the application site may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly. Coughing, sneezing, watery eyes, or throat irritation may occur if you breathe in the dried residue from the medication. If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Stop using this medication and tell your doctor right away if you have any serious side effects, including: blistering/swelling at the application site, increased/unusual pain at the application site. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. PainBloc24® 24 Hour Arthritis Pain Relief 0.5 fl oz. Use for a week, get relief all month Helps block joint pain vs. just dulling pain 24-hour arthritis pain relief Highest concentration of capsaicin available without a prescription Clinically proven ingredient Relief builds with daily use Patented proprietary formula helps block arthritis joint pain at the source of the pain signal Deactivates certain nerve fibers that transmit joint pain signals to the brain 0.25% Capsaicin Odor-free Touch-free, roll-on applicator. Indications: Stop Use Indications: Condition worsens Redness persists, spread or becomes tender Severe burning sensation occurs You experience difficulty breathing or swallowing Symptoms last more than 7 days or clear up and occur again within a few days Irritation develops. When using this product: use only as directed; do not bandage tightly or cover treated area; do not use with heating pad; avoid contact with eyes and mucous membranes; do not apply to wounds, damaged, broken or irritated skin; do not expose the area treated with product to heat or direct sunlight; avoid taking a bath or shower, strenuous exercise or swimming 1 hour before or after applying; a temporary burning sensation and/or redness may occur upon application. This is normal and general stops after a few days of use.

Stop use and ask a doctor if: severe burning sensation occurs; you experience difficulty breathing or swallowing; condition worsens; redness persists, spreads or becomes tender; irritation develops; symptoms last more than 7 days or clear up and occur again within a few days. Pregnancy/breast-feeding warning: If pregnant or breast-feeding, ask a healthcare professional before use. If swallowed, get medical help or contact a Poison Control Center right away. Ingredients: Ingredients: Active Ingredients: Capsaicin (0.25%).

Inactive Ingredients: Alcohol, Diethylene Glycol Monoethyl Ether, Hyaluronate Sodium, Polysorbate 80, Propylene Glycol, Water. Directions: Instructions: Directions - Adults Over 18 Years: Apply to affected area using roller ball until visibly moist. Repeat application, as needed, every 12 to 24 hours. Wash hands with soap and water after each application.

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