Does CBD Affect Blood Work?
This question usually has two different meanings.
The first deals with drug panels and the second deals with routine blood work.
We’ll look at both of them.
The last thing we want is to have our cholesterol spike or white blood cell count drop.
We have good news on that front and we’ll also look at key questions around CBD’s duration in the body.
These are the areas we’ll cover:
- Does CBD show up in a 10-panel drug test
- Does CBD show up in routine blood work
- Does CBD affect blood panel results
- Does CBD affect kidney numbers
- Does CBD affect liver panel
- How long is CBD detectable in urine
Let’s get started.
Does CBD show up in a 10-panel drug test
The first question centers around failing a drug test.
We covered this in detail at our Can CBD make you fail a drug test but the quick answer is…
CBD is not tested in drug panels. Its cousin, THC is. CBD and THC are almost opposite to each other in terms of how they work in the body.
CBD is not psychoactive in that it doesn’t produce a high.
It’s also not addictive (see CBD and addiction), doesn’t build tolerance (see CBD and tolerance), and doesn’t cause withdrawals (see CBD and withdrawals).
We have a more in-depth look at how they oppose each other at our why you must use CBD if you smoke cannabis.
Again, CBD is legal in all 50 states and is not tested on drug panels including the 10-panel drug test.
One note of caution. full spectrum CBD can have up to .03% THC.
This can build up and may make you fail a drug test!
That’s why we focus on CBD isolate. zero THC!
Also, we don’t like the baggage that THC brings with it.
What about routine blood work?
Does CBD show up in routine blood work
No. CBD should not show up in any blood panel work you may have.
First, it’s not tested specifically nor are any metabolites.
None of the tests have a breakout specifically for CBD since it’s not illegal and doesn’t impact other blood panel results.
The one condition is with other medications.
Let’s look at whether CBD affects the results of blood panels next.
Does CBD affect blood panel results
At standard doses (300 mg is the max for neurogenesis in research), the effects of CBD on blood panel results should be negligible.
Research has even looked at higher doses from 600-800 mg for more serious issues like schizophrenia or acute anxiety.
First, what does research show on the safety side where things might be measured?
We’ll start at the physiological level first and work our way down to blood:
The comprehensive review of 132 original studies by Bergamaschi et al. describes the safety profile of CBD, mentioning several properties: catalepsy is not induced and physiological parameters are not altered (heart rate, blood pressure, and body temperature).
As for mental, physical, and gut effects:
Moreover, psychological and psychomotor functions are not adversely affected. The same holds true for gastrointestinal transit, food intake, and the absence of toxicity for nontransformed cells.
Check out CBD and the gut to understand how it can help there.
Let’s drill down into the bloodwork now:
CBD treatment of up to 14 days (3–30 mg/kg b.w. i.p.) did not affect blood pressure, heart rate, body temperature, glucose levels, pH, pCO2, pO2, hematocrit, K+ or Na+ levels, gastrointestinal transit, emesis, or rectal temperature in a study with rodents
We have some key players of our blood panel work there:
- CO2 and Oxygen
- Hematocrit (red blood cell ratio)
- Potassium and sodium
- Gut function
One of the first tests looked at blood and urine tests specifically:
A first pilot study in healthy volunteers in 1973 by Mincis et al. administering 10 mg oral CBD for 21 days did not find any neurological and clinical changes (EEG; EKG).64 The same holds true for psychiatry and blood and urine examinations.
Another study followed up with 30 days of CBD use and found the same results.
Epilepsy patients were monitored for 135 days at 200-300 mg of CBD and the results were the same for blood panels:
Moreover, neurological and physiological examinations were performed, which neither showed signs of CBD toxicity nor severe side effects.
Let’s shift our focus to hormones.
Does CBD affect hormone levels
The endocannabinoid system (which CBD works within) is tasked with balancing three key systems including the endocrine system (hormones).
This is everything from metabolism, sleep, stress response, etc right to the steroidal hormones like estrogen, progesterone, and testosterone.
We did a big review of CBD and estrogen since it’s such a critical supporter of serotonin function (see CBD and serotonin).
CBD has been shown to affect these pathways but not in an abnormal way.
For example, CBD was shown to reduce resetin which is a hormone tied to obesity. (see CBD and weight during perimenopause or CBD and appetite).
We cannot find human studies of CBD affecting hormone profiles at doses common in research (300-600 mg).
THC has been shown to suppress the entire suite of steroidal hormones which has important ramifications.
Since CBD has shown opposing effects to THC in almost every pathway, we wouldn’t be surprised if it constrains THC’s effect there as well. We need more research.
Let’s look at the two workhorses for our urine and blood panels respectively.
Does CBD affect kidney numbers
It’s hard to separate out CBD from cannabis or THC in the studies.
There are studies where CBD is used to protect the kidney when under assault such as:
The cannabidiol treatment had a protective effect against inflammation and oxidative damage in the kidney ischemia/reperfusion model.
If standard kidney function as normal CBD doses (300-600 mg) was impaired, we would expect to see it in the urine panels above and we didn’t.
We look forward to more specific kidney testing. Always work with your doctor or naturopath for any supplement especially if you have kidney issues.
Does CBD affect liver panel
First, understand that the liver is the primary site of CBD metabolism.
In fact, it uses a very common thoroughfare called P450 that up to 60% of common medications also use.
For this reason, it can interact with other medications and this is why you should work with your doctor or naturopath if you’re on other medications with any supplement.
It can slow down or increase the absorption of the other medication.
There was a study on mice that showed potential liver issues from CBD but the doses given were so high (approximately 3200 mg for a 160 pound human) that it’s nonsensical.
You can die from too much water and Tylenol is leading cause liver failure in the US.
If standard doses had issues on the liver, we would see it in the blood panels referenced above in studies.
In fact, there’s evidence of CBD’s benefits for liver function when under duress.
Mice were given a poison essentially which would severely impact the liver and brain.
The effects of CBD:
Increased plasma levels of ammonia, bilirubin, and liver enzymes, as well as enhanced 5-HT levels in thioacetamide-treated mice, were normalized following cannabidiol administration.
The keyword there is “normalized”. Not boosted or reduced. We see this throughout other key pathways such as serotonin, GABA, and even cancer!
Some practical questions.
How long is CBD detectable in urine and blood
So. we already addressed that CBD will not cause you to fail a drug test or even show up on a drug test (if it’s CBD isolate).
How long does it show?
- The peak level for CBD in the blood in about 4-6 hours.
- The half-life is about 31 hours.
- The elimination period was generally 3-5 days
As for the urine, CBD is generally expelled after about 3 days:
In the urine, unchanged CBD and, to a lesser extent, conjugated CBD were the main excretion products, and about 16% of the total radioactivity was eliminated in 72 h by this route of excretion.
Again, CBD is not part of the standard drug panel as long as it’s CBD isolate only (not full-spectrum which can have THC).
More on CBD safety here.
- Organically grown hemp in the US at an FDA registered farm
- CO2 processed
- 3rd party tested
- No THC!!
- No solvents
- No heavy metals
- No pesticides
- No bacteria
- No mold
We actually test twice since our whole family uses it. Be well!
Always work with a doctor or naturopath with any supplement!
The information provided here is not intended to treat an illness or substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider.
What does research show for CBD's effect on basic lab results? Does CBD Affect Blood Work?
Does CBD Show Up on a Drug Test?
Posted on June 27th, 2020
CBD, or cannabidiol, is a cannabinoid, a compound that is found in all cannabis plants, including the marijuana, and hemp strains of the plant. THC, or tetrahydrocannabinol, is another cannabinoid, found in large concentrations in marijuana plants. This cannabinoid is associated with the psychoactive high you experience when you take marijuana. CBD, on the other hand, gives you many of the same reported benefits of THC use, but without the psychoactive effects. CBD is therefore legal for sale, purchase, and use across the United States. Now, let’s take a deeper look at answering the question: “Does CBD show up on a drug test?”
Does CBD Show Up on a Drug Test?
Studies suggest that CBD does not show up on drug tests. However, the issue is a little more complicated. If, for example, you extract CBD from a marijuana plant, other cannabinoids in that plant could produce a positive drug test. The two most common cannabinoids responsible for positive drug tests are THC and CBN (cannabinol).
Does CBN Show Up On A Drug Test?
Unlike THC, CBN has only mild psychoactive properties. And, like CBD, using CBN has been linked to certain health benefits, including mild improvements in sleep disorders. But CBN use can be complex.
That’s because CBN won’t show up on drug screening tests that are used to detect antibodies in your body. It may, however, show up on tests used to screen for certain compounds. Remember, drug screening tests are not conclusive. If you receive a positive result in a screening, you’ll likely be given a second drug test that detects THC. And CBN will not be detected in these confirmatory tests.
Does THC Show Up On A Drug Test?
Drug tests are designed to detect THC, even a small amount will produce a positive result in both screenings and in other drug tests that can distinguish between THC and the other compounds contained in marijuana.
THC is the reason why marijuana is still considered a controlled substance and is illegal for non-medicinal uses in many states. It is this issue of the legality of THC vs. CBD that makes the question of drug testing even more complex.
The Legal Limit For THC In CBD Products
As mentioned above, CBD will not trigger a positive drug test. However, this is only true when you’re dealing with pure CBD products. But full-spectrum CBD products do contain trace amounts of THC. Currently, the legislation allows CBD products to contain a concentration of no more than 0.3% of THC.
Most CBD products are not entirely pure but are produced within the bounds of the legislated THC concentration. This allows additional cannabinoids to work with the CBD to maximize effects in your body. So, a full-spectrum product is best for your CBD experience. But, even this tiny amount of THC may be detected in both screening and drug tests. So, if your employer conducts regular drug screenings, or if you are a professional athlete, be sure to discuss CBD use before taking any tests.
Some CBD users have found themselves in positions where they’ve been disciplined or even dismissed by an employer due to a positive drug test. Although CBD (with a concentration of less than 0.3% THC) is legal, its use can still be considered grounds for dismissal due to a positive drug test.
While this seems unfair, the reason is this: employees who are using marijuana recreationally can simply say that they are using CBD products. Drug tests cannot discriminate between legal CBD use and illegal marijuana use, so employers may struggle to implement policies and procedures that differentiate between the two.
Now, our full-spectrum, Tanasi CBD products are produced within legislated concentrations of THC. What does that mean for you? The trace amounts of THC may be detected in drug tests and screenings. So we recommend discussing CBD use and your employer’s policies before using any items from our online CBD store. Employers that conduct regular drug testing may not allow for the use of legal CBD products, and it’s best to follow company policies regarding drug use to avoid disciplinary action due to a positive drug test.
Now, if you aren’t subject to regular drug tests, you may still be able to enjoy full-spectrum CBD products. But another factor to consider is how long CBD stays in your body.
How Long Does It Take for CBD (THC) to Leave the Body?
After being consumed or smoked, CBD, CBN, and THC are all broken down, absorbed by your body, and then expelled. This process takes time and the compounds can only be detected in saliva, urine, or blood samples during this process.
Typically, we believe that it takes between 2 and 5 days for these compounds to be entirely metabolized, leave your body, and not show up on a drug test. However, research has shown that this is not always true. Some people simply metabolize the CBD and THC slower than others and it can take weeks before all traces leave their bodies.
It may also depend on the delivery system. Edibles (CBD products that you consume), like pills, gummies, and other consumable sources need to pass through your digestive tract before they can be expelled. This process can take much longer than compounds that are absorbed through the skin, such as CBD oils, ones you consume under the tongue, like CBD tinctures, or like vape juices, which you absorb into the lungs.
The compounds will also disappear from saliva, urine, and blood at different rates. Commonly, saliva will be the first to be clear of CBD and related compounds, whereas blood and urine samples will take longer to be free of cannabinoids.
Which brings us to an important discussion: the type of test being used to detect illegal substances such as marijuana in your body.
What Tests Detect Marijuana Use?
There are a wide variety of tests available that are designed to detect THC. These tests all have one major pitfall in common: they cannot determine the degree of intoxication. This is an important factor when it comes to CBD use, where a positive test may be well within the legal limits of 0.3% for CBD but still trigger a positive test result.
On the other hand, the accepted methods of testing can detect other factors such as the time elapsed since the drug was used as well as the extent of use. These factors can play an important role in differentiating between illegal or recreational marijuana use and legal CBD use.
Saliva testing is widely considered to be an acceptable alternative to other forms of drug testing or screening. However, these tests have a limited window on the time that has elapsed between use and testing. Lab testing is only considered to be reliable within a 72 hour period after use . Saliva tests can detect minute concentrations of THC within this time frame. Tests may need to be confirmed with one of the other types of drug testing methods.
Urine samples can be tested for THC or THC metabolites. Urine testing can detect THC concentrations between 2 and 5 days after use. However, heavy use can be detected up to 2 weeks after use and chronic use up to 30 days or 1 month later. Although urine tests can detect minute concentrations, they are not reliable for determining use volume, or whether your drug use was a one time experience or for an extended period of time.
Blood testing is considered to be invasive and is therefore the least common form of testing for THC. The tests are further limited because the compound leaves the bloodstream relatively quickly after use when compared with saliva, urine, and hair testing. Blood tests for THC are usually accurate for 24 to 72 hours after use but can detect THC for up to 7 days depending on an individual’s blood renewal system. On the other hand, these tests are accurate and are unlikely to produce a false-positive as is the case with saliva testing and urine analysis. It is unlikely that a blood test will be used to detect marijuana or CBD use.
Hair testing has grown in popularity as the preferred method of drug detection. The reason for this is that it provides accurate results for a period of up to 3 months when testing a sample of just 1.5 inches in length.
Accuracy is also key, as false-positives are rare with this testing method. While extremely small concentrations can be detected, the hair test, like other testing methods, can not confirm the concentration of THC levels at the time of use. Still, it does provide a fair evaluation of regular drug use. The testing methods exclude environmental contaminants.
Although CBD will not show up in a drug test, products that contain the regulated amount of 0.3% THC may result in a positive test. With advocacy, we hope that drug tests will become more accurate, detecting relative concentrations of THC to allow you to enjoy legal CBD without fear of repercussions. In the meantime, however, you should speak with an employer before using CBD products; you may also choose a CBD isolate, confirm that it contains no THC, so you can avoid failing a drug test and dealing with the consequences of those unwanted results.
Does CBD show up on a drug test? Studies suggest that CBD does not show up on drug tests. However, the issue is a little more complicated.