Postal Service with delivery occurring 7 days a week, 365 days of the year. The USPS also offers a money-back guarantee if your package is not delivered on time. The Money-Back Guarantee Unlike First Class Mail or Priority Mail, Priority Mail Express has a money-back guarantee if your mailpiece is not delivered by the promised time. The money-back guarantee is contingent on a number of factors including the package drop-off time as well as the origin and destination zip codes. You can access specific guaranteed times here: http://postcalc.usps.com/ServiceCommitments.aspx.
How do I get a refund on late Priority Express Mail? So what happens if your mailpiece is not delivered by the specific commitment time? The USPS handles delivery of your mailpiece, so even if the postage on your mailpiece is printed via the Stamps.com platform, the USPS will be responsible for the refund. For domestic mail, if your Priority Mail Express item is not delivered by the guaranteed time, please visit your local Post Office no later than 30 days from the date the item was mailed. Before you go, please take with you a copy of the receipt from your Print History. If you’re logging into the Stamps.com software, click on “Search” on the left side of your software screen and click on the info box (i) that corresponds to the label/tracking number in the Print History. Click on “Print” to generate a physical copy of your receipt. If you’re logging into Stamps.com Online, click on the “History” tab at the top of your screen and select “Search Print History.” After that, the instructions are the same as for the Stamps.com software.
At the Post Office, the window clerk will ask you to complete PS Form 3533 (Refund for Postage). Please be aware that the form is not available online. Once your claim is verified by the clerk, your claim will be paid by cash or money order. How do I get a refund on late Priority Express Mail for international mail? For international mail, a money-back guarantee is currently available for Priority Mail Express International items sent to the following countries: Australia, Canada, China, France (does not include Corsica and Monaco), Germany, Hong Kong, Israel, Japan, New Zealand, Singapore, South Korea, Spain (does not include the Canary Islands), Sweden, Switzerland, Thailand, United Kingdom. Theres a lot of crazy info out there when it comes to canine joint health and mobility. (Elk antler, anyone?) Arm yourself with the evidence and position your veterinary practice as the trusted source of reliable data. Whether their dogs are old and stiff, young and developing, or couch potatoes, pet owners tend to be highly concerned about canine joints. They're searching online for information on mobility and arthritis, asking each other for recommendations, or going with what's been recommended by their own doctor. Chances are they've already come to you with questions about things like hyper-immune milk factor and Boswellia serrata , but how do you begin to shed light on the veiled world of nutraceuticals? Glucosamine-enriched dog food or shark cartilage supplement? Fortunately, when it comes to evidence-based use of joint supplements in dogs, CVC educator-now Fetch dvm360 conference-Matt Brunke, DVM, CCRP, CVPP, CVA, has the answers. You know pet owners are going to ask you for your opinion. Here's a rundown of the joint supplements getting the most buzz in the pet world these days. Glucosamine hydrochloride is an amino sugar, but it's not involved in the glucose pathway. It's a building block of the cartilage matrix and stimulates growth of cartilage cells. Glucosamine is readily available, cheap and can be given safely to diabetic patients, Dr. Notice that we're discussing glucosamine hydrochloride, here, not glucosamine sulfate. Although glucosamine sulfate is absorbed better, there have been no studies published showing that glucosamine sulfate actually shows up in synovial tissue after it's been ingested orally. A joint supplement doesn't help if it doesn't get where it needs to be. A loading dose of two times maintenance for four to six weeks is required for glucosamine hydrochloride to reach therapeutic levels, Dr. Maintenance is 500 to 1,000 mg for a 75-lb dog, which works out to about 15 mg/kg. A randomized, double-blind, positive-controlled, multicenter trial assessed 35 dogs with confirmed osteoarthritis of the hip or elbow for their response to orally administered glucosamine hydrochloride and chondroitin sulfate. Although onset of efficacy was slower than carprofen, dogs treated with glucosamine-chondroitin showed statistically significant improvements in pain scores, severity and weightbearing by day 70.1.
This supplement works by inhibiting cartilage-destroying enzymes, but it's difficult to source and extract, which raises the cost. Chondroitin is a large molecule with variable absorption, Dr. Brunke says, though some companies produce a low-molecular-weight version that can increase absorption from the gastrointestinal tract. Chondroitin requires a loading dose similar to glucosamine, and the standalone dosage is the same as glucosamine. When given with glucosamine, chondroitin has a synergistic effect and has been shown to lessen inflammation if given before a joint injury in dogs, Dr. ASUs protect cartilage matrix against damage by inhibiting key mediators of the structural changes that take place in osteoarthritis,2 and they stimulate healing of osteochondral defects in the canine knee, possibly by increasing transforming growth factor (TGF)-beta in the tissues.3 The dosage used in the studies referenced was one 300-mg capsule ASUs every three days, but Dr. Brunke recommends daily administration based on body weight. He adds that the efficacy of ASUs is similar to NSAIDs in dogs, but they have a delay in onset similar to glucosamine and chondroitin. When combined with glucosamine and chondroitin, ASUs modify and amplify the actions of each and reduce the amount of chondroitin required.
Omega-3s are known to support heart health and joints, improve kidneys and boost the immune system, but the dosage for each condition varies.