But some products can still pose risks, especially when they interact with other products a consumer might be taking. And with all the various medications and supplements on the market, the combinations are endless. Statistics show that over 170 million US adults take supplements, ranging from garden-variety vitamins to exotic herbal mixtures. In fact, nearly 25% of Americans report concurrently taking a prescription medication with a dietary supplement. But unlike medications, the FDA doesn’t review nutritional or dietary supplements for safety or effectiveness before they’re sold.
Using artificial intelligence to make searches more efficient. Seattle’s Allen Institute for Artificial Intelligence, or AI2, says it is taking the legwork out of the daunting process of gleaning through possible interactions. Using its Semantic Scholar academic search engine, Supp.AI, the searchable database indexes 4,650 supplements and drugs from Abbokinase to Zytiga. The free tool offers research findings on more than 56,000 interactions from over the years. According to the report, “More than half of US adults use dietary supplements. Supplements include vitamins, minerals, enzymes, and other herbal and animal products. Although the pharmacological effects of many supplement ingredients remain uncertain due to limited FDA regulation, there has been substantial documentation of adverse interactions between supplements and pharmaceutical drugs. However, these studies largely rely on manual curation of the literature, and are slow and expensive to produce and update. It is also difficult to aggregate their results, and researchers, clinicians, and consumers can lack appropriate and up-to-date information to make informed decisions about supplement use. Consumer-facing websites such as the NIH Office of Dietary Supplements or WebMD provide facts about some common supplements, but this information can be incomplete.
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